As health-related use of cannabis is increasingly legalized worldwide, a much better understanding of the health-related and hazardous effects of this drug is crucial. The discomfort associated with rheumatic ailments is viewed as a prevalent indication for medicinal cannabis in a variety of nations. Therefore far, preliminary clinical trials have explored the effects of cannabis on rheumatoid arthritis, osteoarthritis and fibromyalgia preliminary proof has also located an association among the cannabinoid technique and other rheumatic situations, like systemic sclerosis and juvenile idiopathic arthritis. The possible medicinal effects of cannabis could be attributable to its influence on the immune technique, as it exerts an immunomodulatory impact on a variety of immune cells, like T cells, B cells and macrophages. Nevertheless, the offered proof is not but adequate to assistance the recommendation of cannabinoid remedy for rheumatic ailments.
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